Article
The association between heterozygosity for UGT1A1*6, UGT1A1*28, and variation in the serum total-bilirubin level in healthy young Japanese adults.
Genetic testing and molecular biomarkers - 1 Jun 2013
Moriya Hiroyuki, Saito Katsuhiko, Helsby Nuala, Sugino Shigekazu, Yamakage Michiaki, Takasaki Masahiko, Kato Hidenori, Kurosawa Nahoko
Abstract excerpt
AIMS: Considerable variations in the serum total-bilirubin concentrations are observed in healthy subjects. Both sex and the UGT1A1 homozygous genotypes,*6/*6 and *28/*28, are known to influence this variation. However, currently, there is no consensus on the relationship of the heterozygous genotypes *1/*6, *1/*28, or *6/*28 and interindividual variation in the serum total-bilirubin levels. In the present study,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.