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Article

Body fat percentage is a major determinant of total bilirubin independently of UGT1A1*28 polymorphism in young obese.

PloS one - 1 Jan 2014

Belo Luís, Nascimento Henrique, Kohlova Michaela, Bronze-da-Rocha Elsa, Fernandes João, Costa Elísio, Catarino Cristina, Aires Luísa, Mansilha Helena Ferreira, Rocha-Pereira Petronila, Quintanilha Alexandre, Rêgo Carla, Santos-Silva Alice

Abstract excerpt

OBJECTIVES: Bilirubin has potential antioxidant and anti-inflammatory properties. The UGT1A1*28 polymorphism (TA repeats in the promoter region) is a major determinant of bilirubin levels and recent evidence suggests that raised adiposity may also be a contributing factor. We aimed to study the interaction between UGT1A1 polymorphism, hematological and anthropometric variables with total bilirubin levels in young...

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PMID: 24901842
DOI: 10.1371/journal.pone.0098467
PMCID: PMC4046990

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