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The transcription factor HAND2 up-regulates transcription of the IL15 gene in human endometrial stromal cells

22 May 2020

Abstract excerpt

Cyclic changes of the human endometrium, such as proliferation, secretion, and decidualization, occur during regular menstrual cycles. Heart– and neural crest derivatives–expressed transcript 2 (HAND2) is a key transcription factor in progestin-induced decidualization of human endometrial stromal cells (ESCs). It has been suggested that HAND2 regulates interleukin 15 (IL15), a key immune factor required for the...

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PMID: 32444497
DOI: 10.1074/jbc.ra120.012753

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