Article
GG genotype of cyclin D1 G870A polymorphism is associated with non-cardiac gastric cancer in a high-risk region of China.
Scandinavian journal of gastroenterology - 1 Jan 2008
Jia Ai, Gong Jun, Li Yingchao, Hao Zhiming, Chang Xinming, Dai Fei, Yu Bing
Abstract excerpt
OBJECTIVE: Cyclin D1 (CCND1) is a regulatory protein involved in the cell cycle of both normal and neoplastic cells. Polymorphism of this gene at codon 242 in exon 4 (A870G) has an impact on the risk of several human cancers. The purpose of this study was to study the relation between the CCND1 A870G gene polymorphism and the risk of non-cardiac gastric cancer in a Chinese population. MATERIAL AND METHODS: The...
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