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Article

M protein conserved region antibodies opsonise multiple strains of Streptococcus pyogenes with sequence variations in C-repeats.

Research in microbiology - 1 May 2005

Vohra Harpreet, Dey Nilay, Gupta Shivali, Sharma Anil K, Kumar Rajesh, McMillan David, Good Michael F

Abstract excerpt

The development of a group A streptococcal (GAS) vaccine has focused on the M protein, a major virulence factor. Antibodies against the amino terminal domain of the M protein are generally protective but only provide type-specific immunity. J14, a 29-mer peptide sequence which contains a conserved epitope from the C-repeat region of the M protein, offers the possibility of a vaccine which will elicit protective...

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Source

Identifiers

PMID: 15862457
DOI: 10.1016/j.resmic.2004.12.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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