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Article

Immunogenicity and protective efficacy of the alpha C protein of group B streptococci are inversely related to the number of repeats

1 Dec 1997

Abstract excerpt

Infection by group B streptococci (GBS) is an important cause of bacterial disease in neonates. Alpha C protein is a protective cell surface-associated protein of GBS. This protein contains a repeat region flanked by N and C termini. Variable expression of tandem repeating units of alpha C proteins had been found among clinical isolates of GBS. We examined the effect of the number of repeats on the immunogenicity...

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Identifiers

PMID: 9393818
DOI: 10.1128/iai.65.12.5216-5221.1997

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