Article
emm and C-repeat region molecular typing of beta-hemolytic Streptococci in a tropical country: implications for vaccine development.
Journal of clinical microbiology - 1 Aug 2009
Steer Andrew C, Magor Graham, Jenney Adam W J, Kado Joseph, Good Michael F, McMillan David, Batzloff Michael, Carapetis Jonathan R
Abstract excerpt
We designed a study to investigate the molecular epidemiology of group A streptococcal (GAS) and group C and G streptococcal (GCS and GGS) disease in Fiji, a country which is known to have a high burden of streptococcal disease. Molecular typing of the N-terminal portion (emm typing) of the M protein was performed with 817 isolates (535 GAS and 282 GCS/GGS). We also performed genotyping of the C-repeat region in...
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