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Article

A misfolded protein conformation is not a sufficient condition for in vivo glucosylation by the UDP-Glc:glycoprotein glucosyltransferase.

The EMBO journal - 15 Oct 1998

Fernández F, D'Alessio C, Fanchiotti S, Parodi A J

Abstract excerpt

A key element in the quality control of glycoprotein folding is the UDP-Glc:glycoprotein glucosyltransferase (GT), which in cell-free assays exclusively glucosylates misfolded glycoproteins. In order to test if such a protein conformation is a sufficient condition for in vivo glucosylation of all N-linked oligosaccharides by GT, a Schizosaccharomyces pombe double mutant (gls2/alg6) was constructed. With this...

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Identifiers

PMID: 9774332
DOI: 10.1093/emboj/17.20.5877
PMCID: PMC1170915

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Source receipt: pubmed, retrieved 7 Sept 2026.

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