Article
A quasi-atomic model of human adenovirus type 5 capsid.
The EMBO journal - 4 May 2005
Fabry Céline M S, Rosa-Calatrava Manuel, Conway James F, Zubieta Chloé, Cusack Stephen, Ruigrok Rob W H, Schoehn Guy
Abstract excerpt
Adenoviruses infect a wide range of vertebrates including humans. Their icosahedral capsids are composed of three major proteins: the trimeric hexon forms the facets and the penton, a noncovalent complex of the pentameric penton base and trimeric fibre proteins, is located at the 12 capsid vertices. Several proteins (IIIa, VI, VIII and IX) stabilise the capsid. We have obtained a 10 A resolution map of the human...
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