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Cryo-EM structure of enteric adenovirus HAdV-F41 highlights structural variations among human adenoviruses

24 Feb 2021

Abstract excerpt

Enteric adenoviruses, one of the main causes of viral gastroenteritis in the world, must withstand the harsh conditions found in the gut. This requirement suggests that capsid stability must be different from that of other adenoviruses. We report the 4-Å-resolution structure of a human enteric adenovirus, HAdV-F41, and compare it with that of other adenoviruses with respiratory (HAdV-C5) and ocular (HAdV-D26)...

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PMID: 33627423
DOI: 10.1126/sciadv.abd9421

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