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Identification of a novel structural motif and overexpression of key transcripts elucidated in Adenovirus 10

2025-09-20

Abstract excerpt

Adenoviruses are widely used as vectors for subunit vaccines and oncolytic therapies. Efficient vectors must infect target cells and deliver therapeutic transgenes at high levels. Species D adenoviruses, such as human adenovirus type 10 (HAdV-D10), are promising candidates due to low seroprevalence in humans. Here, we present the cryo-electron microscopy structure of the HAdV-D10 capsid alongside transcriptomic pr...

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Literature Corpus work
3c14236a-9e16-5715-88b0-7767f82a0b30
DOI
10.1101/2025.09.20.677498
Open publication

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Identification of a novel structural motif and overexpression of key transcripts elucidated in Adenovirus 10DOI 10.1101/2025.09.20.677498
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