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Article

Atomic Structure of Human Adenovirus by Cryo-EM Reveals Interactions Among Protein Networks

26 Aug 2010

Abstract excerpt

Construction of a complex virus may involve a hierarchy of assembly elements. Here, we report the structure of the whole human adenovirus virion at 3.6 angstroms resolution by cryo-electron microscopy (cryo-EM), revealing in situ atomic models of three minor capsid proteins (IIIa, VIII, and IX), extensions of the (penton base and hexon) major capsid proteins, and interactions within three protein-protein...

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PMID: 20798312
DOI: 10.1126/science.1187433

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