Article
Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C.
Blood - 15 Aug 2005
Butera David, Marukian Svetlana, Iwamaye Amy E, Hembrador Edgardo, Chambers Thomas J, Di Bisceglie Adrian M, Charles Edgar D, Talal Andrew H, Jacobson Ira M, Rice Charles M, Dustin Lynn B
Abstract excerpt
Chronic infection with the hepatitis C virus (HCV) is associated with failures of T-cell-mediated immune clearance and with abnormal B-cell growth and activation. We examined the levels of chemokines that bind to CXC chemokine receptor 3 (CXCR3) to determine whether such chemokines might play a role in the failure of the immune system to clear HCV infection. Elevations in CXC ligand 9 (CXCL9), CXCL10, and CXCL11...
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