Article
Chemokines in the immunopathogenesis of hepatitis C infection.
Hepatology (Baltimore, Md.) - 1 Feb 2009
Heydtmann Mathis, Adams David H
Abstract excerpt
Chronic infection with the hepatitis C virus, a noncytopathic hepatotropic RNA virus, affects over 170 million people worldwide. In the majority of cases, neither the early innate immune response nor the later adaptive immune response succeeds in clearing the virus, and the infection becomes chronic. Furthermore, in many patients, the ineffective inflammatory response drives fibrogenesis and the development of...
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