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Integrated bioinformatics analysis of dendritic cells hub genes reveal potential early tuberculosis diagnostic markers

8 Sept 2023

Abstract excerpt

BACKGROUND: Dendritic cells (DCs) are most potent antigen-processing cells and play key roles in host defense against Mycobacterium tuberculosis (MTB) infection. In this study, hub genes in DCs during MTB infection were first investigated using bioinformatics approaches and further validated in Monocyte-derived DCs. METHODS: Microarray datasets were obtained from Gene Expression Omnibus (GEO) database. Principal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37684607
DOI: 10.1186/s12920-023-01646-0

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