Article
Marker-assisted introgression of trypanotolerance QTL in mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2005
Koudandé O Delphin, van Arendonk Johan A M, Iraqi Fuad
Abstract excerpt
A marker-assisted introgression (MAI) experiment was conducted to use genetic markers to transfer each of the three trypanotolerance QTL from a donor mouse strain, C57BL/6, into a recipient mouse strain, A/J. We used a backcross strategy that consisted of selecting two lines, each carrying two of the donor QTL alleles through the backcross (BC) phase. At the fourth BC generation, single-carrier animals were...
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