Article
High resolution mapping of trypanosomosis resistance loci Tir2 and Tir3 using F12 advanced intercross lines with major locus Tir1 fixed for the susceptible allele.
BMC genomics - 22 Jun 2010
Nganga Joseph K, Soller Morris, Iraqi Fuad A
Abstract excerpt
BACKGROUND: Trypanosomosis is the most economically important disease constraint to livestock productivity in Africa. A number of trypanotolerant cattle breeds are found in West Africa, and identification of the genes conferring trypanotolerance could lead to effective means of genetic selection for trypanotolerance. In this context, high resolution mapping in mouse models are a promising approach to identifying...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Female
- Genetic Loci
- Genetic Predisposition to Disease
- Genotype
- Hybridization, Genetic
- Immunity, Innate
- Male
- Mice