Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis.

American journal of human genetics - 1 Jun 2005

Weller Sabine, Cajigas Ivelisse, Morrell James, Obie Cassandra, Steel Gary, Gould Stephen J, Valle David

Abstract excerpt

Matsumoto and colleagues recently identified PEX26 as the gene responsible for complementation group 8 of the peroxisome biogenesis disorders and showed that it encodes an integral peroxisomal membrane protein with a single C-terminal transmembrane domain and a cytosolic N-terminus that interacts with the PEX1/PEX6 heterodimer through direct binding to the latter. They proposed that PEX26 functions as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Cytosol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Peroxisomal Disorders

Share to Peroxisome-Targeting Signal 1 Receptor

Share to Peroxisomes

Share to Protein Isoforms

Share to Receptors, Cytoplasmic and Nuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 15858711
DOI: 10.1086/430637
PMCID: PMC1196456

Genes

PEX26
PEX1
PEX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis.PMID 15858711Read ↗

PEX6 Mutations in Peroxisomal Biogenesis DisordersSemantic proximity Read ↗

Functional domains and dynamic assembly of the peroxin Pex14p, the entry site of matrix proteins.Semantic proximity Read ↗

Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation.Semantic proximity Read ↗

The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes.Semantic proximity Read ↗

Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export.Semantic proximity Read ↗

Arabidopsis ABERRANT PEROXISOME MORPHOLOGY9 is a peroxin that recruits the PEX1-PEX6 complex to peroxisomes.Semantic proximity Read ↗

A pex1 missense mutation improves peroxisome function in a subset of Arabidopsis pex6 mutants without restoring PEX5 recyclingSemantic proximity Read ↗

Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complex.Semantic proximity Read ↗

PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import.Semantic proximity Read ↗

PEX1 <sup>G843D</sup> remains functional in peroxisome biogenesis but is rapidly degraded by the proteasomeSemantic proximity Read ↗

Genotype-phenotype correlation in PEX5-deficient peroxisome biogenesis defective cell lines.Semantic proximity Read ↗

The peroxisome biogenesis factors pex4p, pex22p, pex1p, and pex6p act in the terminal steps of peroxisomal matrix protein import.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.