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Article

Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation.

Journal of cell science - 1 Sept 2006

Matsuzono Yuji, Matsuzaki Takashi, Fujiki Yukio

Abstract excerpt

The peroxin Pex19p functions in peroxisomal membrane assembly. Here we mapped functional domains of human Pex19p comprising 299 amino acids. Pex19p mutants deleted in the C-terminal CAAx farnesylation motif, the C-terminal 38 amino acid residues and the N-terminal 11 residues, maintained peroxisome-restoring activity in pex19 cells. The sequence 12-261 was essential for re-establishing peroxisome activity. Pex19p...

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Identifiers

PMID: 16895967
DOI: 10.1242/jcs.03100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation.PMID 16895967Read ↗

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