Article
Reduced sleep in Drosophila Shaker mutants.
Nature - 28 Apr 2005
Cirelli Chiara, Bushey Daniel, Hill Sean, Huber Reto, Kreber Robert, Ganetzky Barry, Tononi Giulio
Abstract excerpt
Most of us sleep 7-8 h per night, and if we are deprived of sleep our performance suffers greatly; however, a few do well with just 3-4 h of sleep-a trait that seems to run in families. Determining which genes underlie this phenotype could shed light on the mechanisms and functions of sleep. To do so, we performed mutagenesis in Drosophila melanogaster, because flies also sleep for many hours and, when sleep...
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