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Article

Increased volatile anesthetic requirement in short-sleeping Drosophila mutants.

Anesthesiology - 1 Feb 2009

Weber Bernd, Schaper Christian, Bushey Daniel, Rohlfs Marko, Steinfath Markus, Tononi Giulio, Cirelli Chiara, Scholz Jens, Bein Berthold

Abstract excerpt

BACKGROUND: Anesthesia and sleep share physiologic and behavioral similarities. The anesthetic requirement of the recently identified Drosophila mutant minisleeper and other Drosophila mutants was investigated. METHODS: Sleep and wakefulness were determined by measuring activity of individual wild-type and mutant flies. Based on the response of the flies at different concentrations of the volatile anesthetics...

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Identifiers

PMID: 19164958
DOI: 10.1097/ALN.0b013e3181942df2
PMCID: PMC2776714

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Source receipt: pubmed, retrieved 7 Sept 2026.

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