Article
Genetic Dissociation of Daily Sleep and Sleep Following Thermogenetic Sleep Deprivation in Drosophila.
Sleep - 1 May 2016
Dubowy Christine, Moravcevic Katarina, Yue Zhifeng, Wan Joy Y, Van Dongen Hans P A, Sehgal Amita
Abstract excerpt
STUDY OBJECTIVES: Sleep rebound-the increase in sleep that follows sleep deprivation-is a hallmark of homeostatic sleep regulation that is conserved across the animal kingdom. However, both the mechanisms that underlie sleep rebound and its relationship to habitual daily sleep remain unclear. To address this, we developed an efficient thermogenetic method of inducing sleep deprivation in Drosophila that produces...
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