Article
Association between three functional polymorphisms of the dopamine D2 receptor gene and polydipsia in schizophrenia.
The international journal of neuropsychopharmacology - 1 Jun 2005
Matsumoto Chima, Shinkai Takahiro, De Luca Vincenzo, Hwang Rudi, Hori Hiroko, Lanktree Matthew, Ohmori Osamu, Kennedy James L, Nakamura Jun
Abstract excerpt
The underlying pathophysiology of polydipsia in schizophrenia is poorly understood. However, several studies suggest there may be a genetic predisposition to polydipsia, including our previous study demonstrating familial concordance of polydipsia among first-degree relatives with schizophrenia. Antipsychotic medications may contribute to the development of polydipsia and studies show that dopamine D2 receptors...
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