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Article

Association analysis between the C-1291G polymorphism in the promoter region of the adrenergic alpha2A receptor gene and polydipsia in schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 30 Apr 2009

Yamaguchi Wakana, Shinkai Takahiro, Inoue Yoshiaki, Utsunomiya Kensuke, Sakata Shinichi, Fukunaka Yuko, Yamada Kenji, Chen Hsin-I, Hwang Rudi, Ohmori Osamu, Nakamura Jun

Abstract excerpt

Several lines of studies have shown the existence of an important inhibitory mechanism for the control of water intake involving adrenergic alpha2A receptors (ADRA2A). A human study using patients with schizophrenia demonstrated an exacerbation of polydipsia by the administration of clonidine, an ADRA2A-agonist, and a relief of polydipsia by mianserin, an ADRA2A-antagonist, suggesting the involvement of the...

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Share to Adrenergic alpha-Agonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19439247
DOI: 10.1016/j.pnpbp.2009.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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