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Article

A novel transglutaminase activator forms a complex with type 1 transglutaminase.

Oncogene - 21 Apr 2005

Sturniolo Michael T, Chandraratna Roshantha A S, Eckert Richard L

Abstract excerpt

Type I transglutaminase is a plasma membrane-anchored intracellular protein-protein crosslinking enzyme that is responsible for assembly of the keratinocyte cornified envelope during terminal keratinocyte differentiation. We recently described a novel protein, TIG3, that when expressed in keratinocytes causes increased transglutaminase activity and keratinocyte cell death. However, the mechanism of activation of...

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PMID: 15846304
DOI: 10.1038/sj.onc.1208392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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