Article
A three-dimensional model of the human transglutaminase 1: insights into the understanding of lamellar ichthyosis.
Journal of molecular modeling - 1 Jan 2007
Boeshans Karen M, Mueser Timothy C, Ahvazi Bijan
Abstract excerpt
The stratum corneum, the outer layer of the epidermis, serves as a protective barrier to isolate the skin from the external environment. Keratinocyte transglutaminase 1 (TGase 1) catalyzes amide crosslinking between glutamine and lysine residues on precursor proteins forming the impermeable layer...
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