Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion.

doi:10.1083/jcb.119.2.463

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Article

Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion.

The Journal of cell biology - 1 Oct 1992

Gentile V, Thomazy V, Piacentini M, Fesus L, Davies P J

Abstract excerpt

Tissue transglutaminase is a cytosolic enzyme whose primary function is to catalyze the covalent cross-linking of proteins. To investigate the functions of this enzyme in physiological systems, we have established lines of Balb-C 3T3 fibroblasts stably transfected with a constitutive tissue transglutaminase expression plasmid. Several cell lines expressing high levels of catalytically active tissue...

Topics

3T3 Cells
Animals
Apoptosis
Butyrates
Butyric Acid
Cell Adhesion
Cell Division
Enzyme Induction
Fibroblasts
Fluorescent Antibody Technique
Genetic Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred BALB C

Morphogenesis

Peptides

Phenotype

Recombinant Proteins

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 1356992
DOI: 10.1083/jcb.119.2.463
PMCID: PMC2289646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1356992-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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