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Article

A novel class of dual-family immunophilins.

The Journal of biological chemistry - 1 Jul 2005

Adams Brian, Musiyenko Alla, Kumar Rajinder, Barik Sailen

Abstract excerpt

Immunophilins are protein chaperones with peptidylprolyl isomerase activity that belong to one of two large families, the cyclosporin-binding cyclophilins (CyPs) and the FK506-binding proteins (FKBPs). Each family displays characteristic and conserved sequence features that differ between the two families. We report a novel group of dual-family immunophilins that contain both CyP and FKBP domains for which we...

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Identifiers

PMID: 15845546
DOI: 10.1074/jbc.M500990200
PMCID: PMC2270415

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