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Article

A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae.

Molecular bioSystems - 1 Oct 2012

Singh-Babak Sheena D, Shekhar Tanvi, Smith Andrew M, Giaever Guri, Nislow Corey, Cowen Leah E

Abstract excerpt

Fungi rely on regulatory networks to coordinate sensing of environmental stress with initiation of responses crucial for survival. Antifungal drugs are a specific type of environmental stress with broad clinical relevance. Small molecules with antifungal activity are ubiquitous in the environment, and are produced by a myriad of microbes in competitive natural communities. The echinocandins are fungal...

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PMID: 22751784
DOI: 10.1039/c2mb25107h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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