Article
Cross-Reactive Surface Epitopes on Chondroitin Sulfate A-AdherentPlasmodium falciparum-Infected Erythrocytes Are Associated with Transcription ofvar2csa
21 Apr 2005
Abstract excerpt
Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated by P. falciparum erythrocyte membrane protein 1 (PfEMP1), a variant parasite protein expressed on the surface of IE and encoded by var genes. Rabbit antiserum was generated against the CSA-adherent P. falciparum line CS2, in which the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
