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Article

Requirement of Cul3 for axonal arborization and dendritic elaboration in Drosophila mushroom body neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Apr 2005

Zhu Sijun, Perez Rosanne, Pan Marc, Lee Tzumin

Abstract excerpt

Cul3 belongs to the family of cullin proteins, which function as scaffold proteins of E3 ubiquitin ligase complexes. Here we show cell-autonomous involvement of Cul3 in axonal arborization and dendritic elaboration of Drosophila mushroom body neurons. Cul3 mutant neurons are defective in terminal morphogenesis of neurites. Interestingly, mutant axons often terminate around branching points. In addition, dendritic...

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Identifiers

PMID: 15843622
DOI: 10.1523/JNEUROSCI.0149-05.2005
PMCID: PMC6724961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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