Article
A newly identified RET proto-oncogene polymorphism is found in a high number of endocrine tumor patients.
Human genetics - 1 Jul 2005
Gartner Wolfgang, Mineva Ivelina, Daneva Teodora, Baumgartner-Parzer Sabina, Niederle Bruno, Vierhapper Heinrich, Weissel Michael, Wagner Ludwig
Abstract excerpt
Multiple RET proto-oncogene transcripts, due to genomic variations and alternate splicing, have been described. To investigate endocrine tumor tissue characteristic RET proto-oncogene expression, we performed quantitative RT-PCR, Northern blot and Southern blot analyses of benign and malignant endocrine-derived tissues. We newly describe RET proto-oncogene expression in carcinoid-, gastrinoma- and...
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