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Article

Common alleles of predisposition in endocrine neoplasia.

Current opinion in genetics & development - 1 Jun 2010

Eng Charis

Abstract excerpt

The identification of germline high penetrance gain-of-function mutations in the RET proto-oncogene as causative of multiple endocrine neoplasia led to accurate molecular diagnosis, predictive testing and gene-informed preventative medicine. Many syndromic endocrine neoplasias fell under this clinically utile model, although not all endocrine neoplasias were accounted for by these high penetrance predisposition...

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Source

Identifiers

PMID: 20211557
DOI: 10.1016/j.gde.2010.02.004

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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