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Article

The +49A>G CTLA-4 polymorphism is associated with rheumatoid arthritis in Mexican population.

Clinica chimica acta; international journal of clinical chemistry - 2 May 2010

Muñoz-Valle José F, Valle Yeminia, Padilla-Gutiérrez Jorge R, Parra-Rojas Isela, Rangel-Villalobos Hector, Vázquez del Mercado Mónica, Ledezma-Lozano Iris Y, Villafan-Bernal José R, Armendáriz-Borunda Juan, Pereira-Suárez Ana Laura

Abstract excerpt

BACKGROUND: The Cytotoxic T lymphocyte antigen (CTLA-4) is one of the major susceptibility genes associated with autoimmune diseases. Susceptibility to rheumatoid arthritis (RA) is determined by both environmental and genetic factors. The genetic contribution approaches 50-60%. The association between RA with the +49A>G CTLA-4 polymorphism in the Mexican population was investigated. METHODS: The polymerase chain...

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PMID: 20138855
DOI: 10.1016/j.cca.2010.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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