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Increased keratinocyte proliferation by JUN-dependent expression of PTN and SDF-1 in fibroblasts

20 Apr 2005

Abstract excerpt

In skin, fibroblasts of the connective tissue play a decisive role in epidermal homeostasis and repair by contributing to the regulation of keratinocyte proliferation and differentiation. The AP-1 transcription factor subunit JUN plays a crucial role in this mesenchymal-epithelial interplay by regulating the expression of two critical paracrine-acting cytokines, keratinocyte growth factor (KGF) and...

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Cell Adhesion Molecules Research
Fibroblast Growth Factor Research
Proteoglycans and glycosaminoglycans research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15840658
DOI: 10.1242/jcs.02303

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