Article
c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin.
Cell - 22 Nov 2000
Szabowski A, Maas-Szabowski N, Andrecht S, Kolbus A, Schorpp-Kistner M, Fusenig N E, Angel P
Abstract excerpt
Interactions between mesenchymal and epithelial cells are responsible for organogenesis and tissue homeostasis. This mutual cross-talk involves cell surface proteins and soluble factors, which are mostly the result of regulated transcription. To elucidate dimer-specific functions of the AP-1 family of transcription factors, we reconstituted skin by combining primary human keratinocytes and mouse wild-type,...
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