Article
Inflammatory versus proliferative processes in epidermis. Tumor necrosis factor alpha induces K6b keratin synthesis through a transcriptional complex containing NFkappa B and C/EBPbeta.
The Journal of biological chemistry - 13 Oct 2000
Komine M, Rao L S, Kaneko T, Tomic-Canic M, Tamaki K, Freedberg I M, Blumenberg M
Abstract excerpt
Epidermal keratinocytes respond to injury by becoming activated, i.e. hyperproliferative, migratory, and proinflammatory. These processes are regulated by growth factors and cytokines. One of the markers of activated keratinocytes is keratin K6. We used a novel organ culture system to show that t...
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