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Article

Signalling in inflammatory skin disease by AP-1 (Fos/Jun).

Clinical and experimental rheumatology - 1 Jan 2000

Uluçkan Özge, Guinea-Viniegra Juan, Jimenez Maria, Wagner Erwin F

Abstract excerpt

Skin inflammation is a physiological reaction to tissue injury, pathogen invasion and irritants. During this process, innate and/or adaptive immune cells are activated and recruited to the site of inflammation to either promote or suppress inflammation. The sequential recruitment and activation of immune cells is modulated by a combination of cytokines and chemokines, which are regulated by transcription factors,...

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Source

Identifiers

PMID: 26458100

Genes

CFB
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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Signalling in inflammatory skin disease by AP-1 (Fos/Jun).PMID 26458100Read ↗

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c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin.Semantic proximity Read ↗

Sequestosome 1/p62 enhances chronic skin inflammation.Semantic proximity Read ↗

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AP1 Transcription Factors in Epidermal Differentiation and Skin CancerSemantic proximity Read ↗

Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB.Semantic proximity Read ↗

AP-1 complex activation is a conserved signature of immune system aging and a potential regulator of inflammaging in human and miceSemantic proximity Read ↗

AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasisSemantic proximity Read ↗

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