Article
Identification of functional transcription factor binding sites using closely related Saccharomyces species.
Genome research - 1 May 2005
Doniger Scott W, Huh Juyoung, Fay Justin C
Abstract excerpt
Comparative genomics provides a rapid means of identifying functional DNA elements by their sequence conservation between species. Transcription factor binding sites (TFBSs) may constitute a significant fraction of these conserved sequences, but the annotation of specific TFBSs is complicated by the fact that these short, degenerate sequences may frequently be conserved by chance rather than functional...
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