Article
An association between the methylenetetrahydrofolate reductase (MTHFR) C677T mutation and inflammation markers related to cardiovascular disease.
International journal of cardiology - 28 Apr 2005
Dedoussis George V Z, Panagiotakos Demosthenes B, Pitsavos Christos, Chrysohoou Christina, Skoumas John, Choumerianou Despoina, Stefanadis Christodoulos
Abstract excerpt
BACKGROUND: Prospective studies have identified many markers of systemic inflammation that are powerful predictors of future cardiovascular events. The methylenetetrahydrofolate reductase (MTHFR) C677T genotype, a common polymorphism that induces hyperhomocysteinaemia, has been proposed as a genetic risk factor for cardiovascular disease. In this work, we evaluated the relationship between the levels of...
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