Article
Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2005
Furukawa Toru, Fujisaki Rumi, Yoshida Yoshitaro, Kanai Naomi, Sunamura Makoto, Abe Tadayoshi, Takeda Kazunori, Matsuno Seiki, Horii Akira
Abstract excerpt
DUSP6/MKP-3 is identified as a candidate tumor suppressor gene for pancreatic cancer. The aim of this study was to elucidate the roles of DUSP6 in the pancreatic carcinogenesis through the pancreatic intraepithelial neoplasia and/or intraductal papillary-mucinous neoplasms, both of which are considered to be precursor lesions of invasive carcinoma of the pancreas, by comparing with involvements of other major...
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