Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2014

Schlitter Anna Melissa, Born Diana, Bettstetter Marcus, Specht Katja, Kim-Fuchs Corina, Riener Marc-Oliver, Jeliazkova Petia, Sipos Bence, Siveke Jens T, Terris Benoit, Zen Yoh, Schuster Tibor, Höfler Heinz, Perren Aurel, Klöppel Günter, Esposito Irene

Abstract excerpt

Intraductal papillary neoplasms of the bile duct are still poorly characterized regarding (1) their molecular alterations during the development to invasive carcinomas, (2) their subtype stratification and (3) their biological behavior. We performed a multicenter study that analyzed these issues in a large European cohort. Intraductal papillary neoplasms of the bile duct from 45 patients were graded and subtyped...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma in Situ

Share to Carcinoma, Intraductal, Noninfiltrating

Share to Cholangiocarcinoma

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Neoplasm Grading

Share to Papilloma

Source

Identifiers

PMID: 23828315
DOI: 10.1038/modpathol.2013.112

Genes

CDX2
EGFR
GNAS
KRAS
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.PMID 23828315Read ↗

Intraductal Papillary Neoplasm of Bile Duct: Updated Clinicopathological Characteristics and Molecular and Genetic AlterationsSemantic proximity Read ↗

Intraductal papillary neoplasms of the bile duct consist of two distinct types specifically associated with clinicopathological features and molecular phenotypes.Semantic proximity Read ↗

Genomic and transcriptomic signatures of sequential carcinogenesis from papillary neoplasm to biliary tract cancer.Semantic proximity Read ↗

Tumoral Intraductal Neoplasms of the Bile Ducts Comprise Morphologically and Genetically Distinct EntitiesSemantic proximity Read ↗

Neoplastic Progression in Intraductal Papillary Neoplasm of the Bile Duct.Semantic proximity Read ↗

Perihilar Intraductal Papillary Neoplasm of the Bile Ducts: A Clinicopathologic and Molecular Genetic Study of 27 Cases.Semantic proximity Read ↗

Tumorigenesis and phenotypic characteristics of mucin-producing bile duct tumors: an immunohistochemical approach.Semantic proximity Read ↗

Intraductal Papillary Mucinous Carcinoma Versus Conventional Pancreatic Ductal Adenocarcinoma: A Comprehensive Review of Clinical-Pathological Features, Outcomes, and Molecular Insights.Semantic proximity Read ↗

Molecular characteristics and biological behaviours of the oncocytic and pancreatobiliary subtypes of intraductal papillary mucinous neoplasmsSemantic proximity Read ↗

Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype.Semantic proximity Read ↗

The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes.Semantic proximity Read ↗

Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.