Article
MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer.
FEBS letters - 3 Jan 2011
Hao Jun, Zhang Shuyu, Zhou Yingqi, Hu Xiangui, Shao Chenghao
Abstract excerpt
Both deregulation of tumor-suppressor genes and misexpression of microRNAs (miRNAs) have been implicated in the development of pancreatic cancer, but their relationship during this process remains less clear. Here, we report that the expression of miR-483-3p is strongly enhanced in pancreatic cancer tissues compared to side normal tissues using a miRNA-array differential analysis. Furthermore, DPC4/Smad4 is...
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