Article
Allelic loss studies do not provide evidence for the "endometriosis-as-tumor" theory.
Fertility and sterility - 1 Apr 2005
Prowse Amanda H, Fakis Giannoulis, Manek Sanjiv, Churchman Michael, Edwards Sarah, Rowan Andrew, Koninckx Philippe, Kennedy Stephen, Tomlinson Ian P M
Abstract excerpt
OBJECTIVE: To identify consistent genetic changes in endometriosis samples to determine whether endometriosis lesions are true neoplasms. DESIGN: We analyzed ovarian endometriosis lesions for loss of heterozygosity (LOH) at 12 loci of potential importance (D9S1870, D9S265, D9S270, D9S161, D11S29, D1S199, D8S261, APOA2, PTCH, TP53, D10S541, and D10S1765), including some at which genetic changes were previously...
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