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Article

Familial vesicoureteral reflux: testing replication of linkage in seven new multigenerational kindreds.

Journal of the American Society of Nephrology : JASN - 1 Jun 2005

Sanna-Cherchi Simone, Reese Adam, Hensle Terry, Caridi Gianluca, Izzi Claudia, Kim You Yeun, Konka Anita, Murer Luisa, Scolari Francesco, Ravazzolo Roberto, Ghiggeri Gian Marco, Gharavi Ali G

Abstract excerpt

Vesicoureteral reflux (VUR) (OMIM %193000), a common cause of childhood renal failure, is strongly influenced by hereditary factors. Familial VUR most closely conforms to autosomal-dominant inheritance, but because of variable penetrance and expressivity, large multigenerational pedigrees tractable to linkage analysis have been difficult to ascertain. A single genome-wide study of familial VUR has demonstrated...

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Identifiers

PMID: 15829711
DOI: 10.1681/ASN.2004121034

Genes

ROBO2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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