Article
Functional characterization of full-length TLR3, IRAK-4, and TRAF6 in zebrafish (Danio rerio).
Molecular immunology - 1 May 2005
Phelan Peter E, Mellon Mark T, Kim Carol H
Abstract excerpt
Recently, the zebrafish, Danio rerio, has been recognized as a useful model for infectious disease and immunity. The Toll-like receptor (TLR) family is an evolutionarily conserved component of the innate immune system that responds to specific pathogen-associated molecular patterns (PAMPs) during an infection. This study reports the identification and characterization of a full-length orthologue of mammalian...
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