Article

Toll-like receptor 18 in Labeo rohita: molecular cloning, characterization, and analysis of its response in RBCs, PBLs, and macrophages after PAMP stimulation and bacterial infections

2024-12-01

Abstract excerpt

Toll-like receptors (TLRs) are key pattern recognition receptors (PRRs) that detect pathogen-associated molecular patterns (PAMPs) and elicit broadly acting innate immune responses. This study accomplished the identification, cloning, and sequencing of Labeo rohita TLR18 (LrTLR18). Structurally, LrTLR18 possesses a signal peptide, six leucine-rich repeats (LRRs), an LRR-C-terminal (LRR-CT) domain, a transmembrane...

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Literature Corpus work: 836983d9-b098-5233-b439-a8b920dbe7ef
DOI: 10.1007/s10499-024-01568-3

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