Article
Effects of electron-beam irradiation on whole genome amplification.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2005
Bergen Andrew W, Qi Ying, Haque Kashif A, Welch Robert A, Garcia-Closas Montserrat, Chanock Stephen J, Vaught Jim, Castle Philip E
Abstract excerpt
Electron-beam (E-beam) irradiation, currently being used to sterilize mail addressed to selected ZIP codes in the United States, has significant negative effects on the genomic integrity of DNA extracted from buccal-cell washes. We investigated the yield, composition, and genotyping performance of whole genome amplified DNA (wgaDNA) derived from 24 matched samples of E-beam-irradiated and nonirradiated genomic...
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