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Article

Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration.

Biochemistry - 19 Apr 2005

Baumann Nikola A, Sullivan David P, Ohvo-Rekilä Henna, Simonot Cedric, Pottekat Anita, Klaassen Zachary, Beh Christopher T, Menon Anant K

Abstract excerpt

The mechanism by which newly synthesized sterols are transported from their site of synthesis, the endoplasmic reticulum (ER), to the sterol-enriched plasma membrane (PM) is not fully understood. Studies in mammalian cells suggest that newly synthesized cholesterol is transported to the PM in Golgi-bypassing vesicles and/or via a nonvesicular process. Using the yeast Saccharomyces cerevisiae as a model system, we...

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PMID: 15823040
DOI: 10.1021/bi048296z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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