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Article

Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons.

Genes and immunity - 1 Jun 2005

Hummel S, Schmidt D, Kremeyer B, Herrmann B, Oppermann M

Abstract excerpt

A mutant allele of the chemokine receptor CCR5 gene (CCR5-Delta32), which confers resistance to HIV-1 infection, is believed to have originated from a single mutation event in historic times, and rapidly expanded in Caucasian populations, owing to an unknown selective advantage. Among other candidates, the plague bacillus Yersinia pestis was implicated as a potential source of strong selective pressure on...

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Identifiers

PMID: 15815693
DOI: 10.1038/sj.gene.6364172

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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